Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the ''MBNL1'' gene. It has been implicated in Myotonic dystrophy and has been shown to autoregulate its transcript. Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle.
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